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Tramadol (INN) (pronounced) is an atypical opioid which is a centrally acting analgesic, used for treating moderate to severe pain. It is a synthetic agent, as a 4-phenyl-piperidine analogue of codeine,[1][2] and appears to have actions on the GABAergic, noradrenergic and serotonergic systems. Tramadol was developed by the German pharmaceutical company Grünenthal GmbH in the last years of 1970s and marketed under the trade name Tramal. Grünenthal has also cross licensed the drug to many other pharmaceutical companies that market it under various names.
Miconazole is an imidazole antifungal agent, developed by Janssen Pharmaceutica, and commonly applied topically (to the skin) or mucus membranes to cure fungal infections. It works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes. It can also be used against certain species of Leishmania protozoa (which are a type of unicellular parasite), as these also contain ergosterol in their cell membranes. In addition to its antifungal and antiparasitic actions, it also has some limited antibacterial properties
Cetirizine hydrochloride, an antihistamine, (pronounced) is a major metabolite of hydroxyzine, and a racemic selective H1 receptor antagonist used in the treatment of allergies, hay fever, angioedema, and urticaria. The structural similarity of cetirizine to hydroxyzine, and its derivation from piperazine, attribute similar adverse reactions and properties to other piperazine derivatives.
Cetirizine hydrochloride, an antihistamine, (pronounced) is a major metabolite of hydroxyzine, and a racemic selective H1 receptor antagonist used in the treatment of allergies, hay fever, angioedema, and urticaria. The structural similarity of cetirizine to hydroxyzine, and its derivation from piperazine, attribute similar adverse reactions and properties to other piperazine derivatives.
Cetirizine hydrochloride, an antihistamine, (pronounced) is a major metabolite of hydroxyzine, and a racemic selective H1 receptor antagonist used in the treatment of allergies, hay fever, angioedema, and urticaria. The structural similarity of cetirizine to hydroxyzine, and its derivation from piperazine, attribute similar adverse reactions and properties to other piperazine derivatives.
Cinnarizine is an anti-histaminic drug which is mainly used for the control of vomiting due to motion sickness. It is marketed under the brand Stugeron or Stunarone and is not available over the counter in North America. Cinnarizine was first synthesized by Janssen Pharmaceutica in 1955.
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