Resolving Agent

On a obtenu des analogues phosphoniques optiquement actifs de l'alanine, de la valine, de la leucine, de la phénylalanine et de la phénylglycine, par la résolution des dérivés diphenylamino-1-alkanephosphonates avec l'anhydride de l'acide dibenzoyl-L-tartarique

On a obtenu des analogues phosphoniques optiquement actifs de l'alanine, de la valine, de la leucine, de la phénylalanine et de la phénylglycine, par la résolution des dérivés diphenylamino-1-alkanephosphonates avec l'anhydride de l'acide dibenzoyl-L-tartarique.

Dissolving the racemic mixture of the compound of formula I in a solvent, (b) adding an approximately equimolar amount of an acid selected from di-p-toluoyl-D-(-)-tartaric acid, di-p-toluoyl-L- (+)-tartaric acid and (+)-camphorsulfonic acid to form a mixture containing a salt of compound.

The laevo and dextro forms of dl-3,4-trans-2,2-disubstituted-3,4-diarylchromans and similar derivatives thereof have substantially double the post-coital anti-fertility activity of the known racemic compound.

The laevo and dextro forms of dl-3,4-trans-2,2-disubstituted-3,4-diarylchromans and similar derivatives thereof have substantially double the post-coital anti-fertility activity of the known racemic compound.