Thiazolidinediones or TZDs act by binding to PPARs (peroxisome proliferator-activated receptors), a group of receptor molecules inside the cell nucleus, specifically PPAR (gamma). The normal ligands for these receptors are free fatty acids (FFAs) and eicosanoids. When activated, the receptor migrates to the DNA, activating transcription of a number of specific genes.
Genes upregulated by PPARy can be found in the main article on peroxisome proliferator-activated receptors.
I-thiazolidine-4-carboxylic acid
A compound of formula (I) or a tautomeric form thereof and/or a pharmaceutically acceptable salt thereof, and/or a pharmaceutically acceptable solvate thereof, wherein: A:represents an alkyl group, a substituted or unsubstituted aryl group or an aralkyl group wherein the alkylene or the aryl moiety may be substituted or unsubstituted
Cas No : 2295-31-0
Formula : C3H3NO2S
Molecular Weight : 117.13
Appearance : white / off white Fine Crystal with lumps
Moisture : 1% Max
Solubility : soluble in water
Assay : 99.00 %
Other Impurity : less than 1.00%
Thiazolidinediones or TZDs act by binding to PPARs (peroxisome proliferator-activated receptors), a group of receptor molecules inside the cell nucleus, specifically PPAR? (gamma). The normal ligands for these receptors are free fatty acids (FFAs) and eicosanoids. When activated, the receptor migrates to the DNA, activating transcription of a number of specific genes. Genes up regulated by PPAR can be found in the main article on peroxisome proliferator-activated receptors.
